Recent Updates
Recently added Catalysts

TZD

Phase 2

Type 2 Diabetes Mellitus With Features of Insulin Resistance | Small molecule | Metabolic |China Pharma Holdings, Inc.|Last Updated: Apr 13, 2012

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedPLACEBO_CONTROLLEDDMC
Total Trials1
Total Enrollment49
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT01577095Evaluating the Effects of Electroacupuncture and Rosiglitazone Combined TherapyPHASE2 COMPLETED 49Apr 1, 2006May 1, 2007Apr 13, 20121 Taiwan
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
plasma glucose
Time point(s) at which outcome measure is assessed in one year

The primary endpoint with respect to plasma glucose level after treatment in each group of patients and compare the hypoglycemic activity between these two independent groups.

Secondary Endpoints
plasma free fatty acid (FFA)
Time point(s) at which outcome measure is assessed in one year.
plasma insulin
Time point(s) at which outcome measure is assessed in one yease
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingSINGLE
ModelPARALLEL
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
EA + RosiglitazoneEXPERIMENTAL -
RosiglitazonePLACEBO_COMPARATOR -
Interventions
NameTypeDescription
EA + RosiglitazoneOTHERelectroacupuncture and Rosiglitazone combined therapy on patient of type II DM
TZDDRUGRosiglitazone 8 mg single dose
Unlock Study Design Details
Eligibility Criteria
Age Range20 Years — 65 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * all included native Taiwanese patients, age from 20 to 65 years who diagnosed with type 2 diabetes mellitus within 5 years and keep the same anti-hyperglycemic agents for control diabetes before and during the period in this study * compatible with the diagnostic criteria of d...

Countries:Taiwan
Unlock Eligibility Criteria