Recent Updates
Recently added Catalysts

TS-142

Phase 1

Healthy Subjects | Small molecule | Other |Co-Diagnostics, Inc.|Last Updated: Feb 28, 2025

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedDouble-BlindCONTROLLEDBiomarker
Total Trials1
Total Enrollment61
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT04696952A Study to Evaluate Next Day Effects of TS-142 on Driving Performance in Healthy SubjectsPHASE1 COMPLETED 61Jan 16, 2021Jan 5, 2022Feb 28, 20251 Japan
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Standard deviation of lateral position (SDLP) evaluated by using a driving simulator on day 2
On day 2 at 9 hours post dose
Standard deviation of lateral position (SDLP) evaluated by using a driving simulator on day 9
On day 9 at 9 hours post dose
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingDOUBLE
ModelCROSSOVER
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
TS-142 10 mgEXPERIMENTALPeriod in which subjects received TS-142 10 mg
TS-142 20 mgEXPERIMENTALPeriod in which subjects received TS-142 20 mg
Zopiclone 7.5 mgEXPERIMENTALPeriod in which subjects received Zopiclone 7.5 mg
PlaceboEXPERIMENTALPeriod in which subjects received placebo
Interventions
NameTypeDescription
TS-142DRUGTS-142
ZopicloneDRUGZopiclone
PlaceboDRUGPlacebo
Unlock Study Design Details
Eligibility Criteria
Age Range21 Years — 79 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Males and females aged 21 years or older but less than 80 years at the time of informed consent * Those with a BMI of 18.5 or more and less than 25.0 and a body weight of 40.0 kg or more at screening tests * Have an ordinary driving license and have driven on a daily basis for...

Countries:Japan
Unlock Eligibility Criteria