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ID110521156

Phase 1

Healthy Adult Subjects | Small molecule | Other |Co-Diagnostics, Inc.|Last Updated: Nov 25, 2024

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedDouble-BlindCONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment36
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT06063291Single Ascending Oral Dose Phase 1 Study of ID110521156 in Healthy Adult SubjectsPHASE1 COMPLETED 36Nov 20, 2023Jul 11, 2024Nov 25, 20241 South Korea
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Study Endpoints
Primary Endpoints
AEs/serious AEs (SAEs)
Throughout study duration, up to 9 days

Incidence and severity of ad adverse event

Percentage of subjects with clinically significant change from baseline in vital signs, ECG, safety laboratory test results
Throughout study duration, up to 9 days
Secondary Endpoints
Maximum concentration (Cmax)
Throughout study duration, up to 9 days
Area under the plasma drug concentration-time curve from 0 to last, (AUClast)
Throughout study duration, up to 9 days
Area under the plasma drug concentration-time curve from 0 to infinity (AUCinf)
Throughout study duration, up to 9 days
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Study Design & Arms
AllocationRANDOMIZED
MaskingDOUBLE
ModelSEQUENTIAL
PurposeBASIC_SCIENCE
Treatment Arms
ArmTypeDescription
Cohort 1EXPERIMENTALCohort 1 will consist of 8 healthy subjects who will be randomised to receive a single oral dose of ID110521156 of placebo.
Cohort 2EXPERIMENTALCohort 2 will consist of 8 healthy subjects who will be randomised to receive a single oral dose of ID110521156 of placebo.
Cohort 3EXPERIMENTALCohort 3 will consist of 8 healthy subjects who will be randomised to receive a single oral dose of ID110521156 of placebo.
Cohort 4EXPERIMENTALCohort 4 will consist of 12 healthy subjects who will receive a single oral dose of ID110521156 at fed state and fasted state each.
Interventions
NameTypeDescription
ID110521156DRUGsubjects will receive a single oral dose of IMP. In the morning (all procedures must be performed at the similar clock time) on Day 1
Placebo of ID110521156DRUGsubjects will receive a single oral dose of IMP. In the morning (all procedures must be performed at the similar clock time) on Day 1
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Eligibility Criteria
Age Range19 Years — 50 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Healthy subjects aged 19 to 50 years at the time of Screening. * Body mass index (BMI) within 18.5 to 29.9 kg/m2; and a total body weight ≥ 40 kg, ≤ 90 kg * Evidence of a personally signed and dated informed consent document indicating that the subject has been informed of all...

Countries:South Korea
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