Recent Updates
Recently added Catalysts

HUC2-565-A, HUC2-565-A and HUC2-565-B

Phase 1

Hypertension | Small molecule | Cardiovascular |Co-Diagnostics, Inc.|Last Updated: Oct 1, 2024

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedCONTROLLEDBiomarker
Total Trials1
Total Enrollment46
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT06618079Drug-Drug Interaction Study Between HUC2-565-A and HUC2-565-BPHASE1 ACTIVE NOT_RECRUITING 46Apr 20, 2024Oct 1, 2024Oct 1, 20241 South Korea
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
AUCtau,ss
0-14days

Pharmacokinetic parameter

Cmax,ss
0-14days

Pharmacokinetic parameter

Secondary Endpoints
AUCinf,ss
0-14days
Tmax,ss
0-14days
T1/2,ss
0-14days
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Cohort AEXPERIMENTALEvaluate the effect of S-Amlodipine on the pharmacokinetic properties of Azilsartan under steady states.
Cohort BEXPERIMENTALEvaluate the effect of Azilsartan on the pharmacokinetic properties of S-amlodipine under steady states.
Interventions
NameTypeDescription
HUC2-565-A, HUC2-565-A and HUC2-565-BDRUGCohort A received HUC2-565-A for 5 days, followed by HUC2-565-A and HUC2-565-B for 9 days.
HUC2-565-B, HUC2-565-A and HUC2-565-BDRUGCohort B takes HUC2-565-B for 9 days, then HUC2-565-A and HUC2-565-B for 5 days.
Unlock Study Design Details
Eligibility Criteria
Age Range19 Years — N/A
SexALL
Healthy VolunteersYes
Study Sites1

\[ Inclusion Criteria \] 1. Healthy adult volunteer aged 19 years or older at the pre-study(screening) 2. Volunteer with a body mass index(BMI) of 18.0 kg/m2 or more and 30.0 kg/m2 or less, with a 50kg or more weight at the pre-study(screening) 3. A person who has no chronic disease requiring birth...

Countries:South Korea
Unlock Eligibility Criteria