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DE-104

Phase 2

Open-Angle Glaucoma | Small molecule | Cardiovascular |Co-Diagnostics, Inc.|Last Updated: Mar 16, 2009

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
CONTROLLEDBiomarker
Total Trials1
Total Enrollment -
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00656240To Investigate the Safety and Efficacy of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular HypertensionPHASE2 COMPLETED - - -Mar 16, 20091 Japan
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Study Design & Arms
Treatment Arms
ArmTypeDescription
1EXPERIMENTAL -
2EXPERIMENTAL -
Interventions
NameTypeDescription
DE-104 ophthalmic solutionDRUG -
DE-104 vehicleDRUG -
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Eligibility Criteria
Age Range20 Years — 74 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Diagnosed with primary open-angle glaucoma or ocular hypertension. * Provided signed, written informed consent. * If a subject is a female of childbearing potential, she must utilize reliable contraceptive throughout the study, and must have a negative urine pregnancy test pri...

Countries:Japan
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Competitive Landscape -Open-Angle Glaucoma 9 trials