| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT07479667 | An Antibody-armored Dendritic Cell in Patients With Solid Tumors | PHASE1 | RECRUITING | 8 | — | — | Feb 5, 2026 | Jun 30, 2029 | Mar 18, 2026 | 1 | China |
Adverse events (AEs), serious adverse events (SAEs) and laboratory abnormalities (including their types, frequencies and severity) will be collected. This includes the types, incidence and severity of adverse events, as well as clinically significant abnormal laboratory test results and abnormal physical examination findings that emerge after treatment. Clinical and laboratory adverse events will be primarily graded using Version 6.0 of the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE). The causal relationship between adverse events and the dendritic cell (DC) product will be assessed by investigators in accordance with the causality evaluation criteria specified in the study protocol.
| Arm | Type | Description |
|---|---|---|
| Armored Dendritic Cell Injection | EXPERIMENTAL | - |
| Name | Type | Description |
|---|---|---|
| Armored Dendritic Cell Injection | BIOLOGICAL | Armored dendritic cells are administered via multiple subcutaneous injections. |
Inclusion Criteria: * Aged 18 to 80 years, body weight ≥ 40 kg; male or female, no gender restriction; * ECOG performance status score of 0 to 1; * Histopathologically confirmed solid tumors including pancreatic cancer, colorectal cancer (CRC), gastric cancer and other such malignancies; * Having u...