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Armored Dendritic Cell

Phase 1

Solid Cancers | Monoclonal antibody | Oncology |Co-Diagnostics, Inc.|Last Updated: Mar 18, 2026

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment8
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT07479667An Antibody-armored Dendritic Cell in Patients With Solid TumorsPHASE1 RECRUITING 8Feb 5, 2026Jun 30, 2029Mar 18, 20261 China
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Study Endpoints
Primary Endpoints
Maximum Tolerated Dose
Day 0-Month 5
Evaluate the incidence and severity of adverse events
Day 0-Month 24

Adverse events (AEs), serious adverse events (SAEs) and laboratory abnormalities (including their types, frequencies and severity) will be collected. This includes the types, incidence and severity of adverse events, as well as clinically significant abnormal laboratory test results and abnormal physical examination findings that emerge after treatment. Clinical and laboratory adverse events will be primarily graded using Version 6.0 of the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE). The causal relationship between adverse events and the dendritic cell (DC) product will be assessed by investigators in accordance with the causality evaluation criteria specified in the study protocol.

Secondary Endpoints
Cmax
day 0-day28
antigen-specific T-cell responses
day 0-Month 5
RFS
day 0-Month 24
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Study Design & Arms
AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Armored Dendritic Cell InjectionEXPERIMENTAL -
Interventions
NameTypeDescription
Armored Dendritic Cell InjectionBIOLOGICALArmored dendritic cells are administered via multiple subcutaneous injections.
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Eligibility Criteria
Age Range18 Years — 80 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Aged 18 to 80 years, body weight ≥ 40 kg; male or female, no gender restriction; * ECOG performance status score of 0 to 1; * Histopathologically confirmed solid tumors including pancreatic cancer, colorectal cancer (CRC), gastric cancer and other such malignancies; * Having u...

Countries:China
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