Recent Updates
Recently added Catalysts

AJU-A51

Phase 3

Type2 Diabetes | Small molecule | Metabolic |Co-Diagnostics, Inc.|Last Updated: Mar 26, 2024

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedDouble-BlindCONTROLLEDBiomarker
Total Trials1
Total Enrollment235
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT06329674Efficacy and Safety of AJU-A51 in Type 2 Diabetes Mellitus PatientsPHASE3 COMPLETED 235Apr 27, 2021Jun 13, 2023Mar 26, 20241 South Korea
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Changes in HbA1c
24th week

Changes in HbA1c at the 24th week after the administration of investigational products from the baseline

Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingTRIPLE
ModelPARALLEL
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
AJU-A51+A51R2 placebo+A51R3EXPERIMENTAL -
AJU-A51 placebo+A51R2+A51R3EXPERIMENTAL -
Interventions
NameTypeDescription
AJU-A51DRUGSubjects take the investigational products once a day for 24 weeks.
A51R2DRUGSubjects take the investigational products once a day for 24 weeks.
A51R3DRUGSubjects take the investigational products once a day for 24 weeks.
AJU-A51 PlaceboDRUGSubjects take the investigational products once a day for 24 weeks.
A51R2 PlaceboDRUGSubjects take the investigational products once a day for 24 weeks.
Unlock Study Design Details
Eligibility Criteria
Age Range19 Years — 75 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Those who voluntarily signed the informed consent to participate in this study. * Adults aged 19-75 years. * Those diagnosed with type 2 diabetes mellitus. * 7% ≤ HbA1c ≤ 10.5% * FPG ≤ 270 mg/dL * BMI ≤ 40 kg/㎡ * Subjects able to understand the study, comply with study procedu...

Countries:South Korea
Unlock Eligibility Criteria