Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT00000145 | Age-Related Eye Disease Study (AREDS) | PHASE3 | COMPLETED | 4,757 | — | — | Sep 1, 1990 | Dec 1, 2006 | Jan 23, 2009 | - | — |
| Arm | Type | Description |
|---|---|---|
| 1 | EXPERIMENTAL | Antioxidants |
| 2 | EXPERIMENTAL | Zinc |
| 3 | EXPERIMENTAL | Antioxidants and zinc |
| 4 | NO_INTERVENTION | - |
| Name | Type | Description |
|---|---|---|
| Antioxidants | DIETARY_SUPPLEMENT | 500 milligrams vitamin C; 400 IUs vitamin E; 15 milligrams beta-carotene |
| Zinc | DIETARY_SUPPLEMENT | 80 milligrams zinc oxide; 2 milligrams of cupric oxide |
| Antioxidants and zinc | DIETARY_SUPPLEMENT | 500 milligrams vitamin C; 400 IUs vitamin E; 15 milligrams beta-carotene; 80 milligrams zinc oxide; 2 milligrams of cupric oxide |
Men and women between the ages of 55 and 80 years whose macular status ranges from no evidence of AMD in either eye to relatively severe disease with vision loss in one eye but good vision in the fellow eye (20/30 or better) are eligible for the study provided that their ocular media are clear enoug...