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OCT - clear

Phase 2

Preoperative Skin Preparation | Small molecule | Dermatology |Becton, Dickinson and Company|Last Updated: Apr 23, 2021

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedDouble-BlindPLACEBO_CONTROLLEDBiomarker
Total Trials1
Total Enrollment131
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT03224299Effectiveness of an Antimicrobial Agent for Preoperative Skin PreparationPHASE2 COMPLETED 131Jun 21, 2017Oct 3, 2017Apr 23, 20212 United States
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Study Endpoints
Primary Endpoints
Antimicrobial Activity of the Investigational Products Compared to Control.
10 minutes
Secondary Endpoints
Responder Rate at 6 Hours Post-application
6 hours
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Study Design & Arms
AllocationRANDOMIZED
MaskingTRIPLE
ModelPARALLEL
PurposePREVENTION
Treatment Arms
ArmTypeDescription
Investigational Product #1 (IP1)EXPERIMENTALoctenidine dihydrochloride in isopropyl alcohol in a single-use applicator - clear
Investigational Product #2 (IP2)EXPERIMENTALoctenidine dihydrochloride in isopropyl alcohol in a single-use applicator - tinted
Active ControlACTIVE_COMPARATORChloraPrep® - Hi-Lite Orange® applicator
Negative ControlPLACEBO_COMPARATORsterile 0.9% saline applied with single use applicator
Interventions
NameTypeDescription
OCT - clearDRUGInvestigational Product #1: octenidine dihydrochloride in isopropyl alcohol in a single-use applicator - clear
OCT- tintedDRUGInvestigational product #2: octenidine dihydrochloride in isopropyl alcohol in a single-use applicator - tinted
ChloraPrepOTHERActive Control: ChloraPrep® - Hi-Lite Orange® applicator
SalineOTHERNegative Control: sterile 0.9% saline applied with single use applicator
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersYes
Study Sites2

Inclusion Criteria: * Subjects may be of either sex, at least 18 years of age and of any race. * Subjects must be in good general health. * Subjects must read and sign an Informed Consent Form, Authorization to Use and Disclose Protected Health Information Form, and the List of Restricted Products ...

Countries:United States
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