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Single of Local Anesthetic

Phase 1

Rotator Cuff Injury | Small molecule | Other |Baxter International Inc.|Last Updated: May 19, 2014

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedDouble-BlindACTIVE_CONTROLLED
Total Trials1
Total Enrollment70
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT01355757Post-Operative Quality of Life Evaluation for Different Anesthesia Techniques for Arthroscopic Shoulder SurgeryEARLY_PHASE1 COMPLETED 70Jun 1, 2011Jan 1, 2013May 19, 20141 United States
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Study Endpoints
Primary Endpoints
Quality of Life
24 weeks

To describe rehabilitation achievement and quality of life during 24-week follow-up after shoulder arthroscopy and rotator cuff repair, and identify any association between type of anesthesia procedure and patients' quality of life

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Study Design & Arms
AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Baxter INFUSOR SystemEXPERIMENTALRegional Analgesia INFUSOR system with Patient Control Module for post-operative analgesia
Single Injection of Local AnestheticACTIVE_COMPARATORSingle injection of 20 ml ropivacaine 0.5%
Interventions
NameTypeDescription
Baxter INFUSOR SystemDEVICERegional Analgesia INFUSOR system with Patient Control Module for post-operative analgesia
Single Injection of Local AnestheticDRUGSingle injection of 20 ml ropivacaine 0.5%
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Eligibility Criteria
Age Range18 Years — 75 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: Patients who agree to participate in the study will be asked to sign the informed consent and the HIPAA form. Inclusive criteria are: * 18-75 years of age * ASA physical status I-III * BMI \< 35 kg/m2 Exclusion Criteria: * all open shoulder procedures * patient having diffic...

Countries:United States
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