Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT00736606 | A Study to Assess Co-Administered AZD9056 (Steady State) and Simvastatin (Single Dose) in Healthy Volunteers | PHASE1 | COMPLETED | 12 | — | — | Aug 1, 2008 | Sep 1, 2008 | Dec 2, 2010 | 1 | Germany |
| Arm | Type | Description |
|---|---|---|
| Period 1 | EXPERIMENTAL | simvastatin |
| Period 2 | EXPERIMENTAL | simvastatin + AZD9056 |
| Name | Type | Description |
|---|---|---|
| simvastatin | DRUG | One single dose of 40mg |
| AZD9056 + simvastatin | DRUG | AZD9056: 400 mg od, 8 days simvastatin: one single dose of 40 mg on day 7 |
Inclusion Criteria: * Provision of informed consent prior to any study specific procedures. * Male or female healthy subjects. Females should not be of childbearing potential * Clinically normal physical and laboratory findings as judged by the investigator, including negative test results for drug...