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Tapentadol /mL

Phase 3

Acute Pain | Small molecule | Pain |Assertio Holdings, Inc.|Last Updated: Jan 18, 2020

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment216
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT02081391A Study to Look at Tapentadol Oral Solution in Children and Adolescents in PainPHASE3 COMPLETED 216Feb 19, 2015Mar 14, 2019Jan 18, 202043 United States, United States +41
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Study Design & Arms
AllocationRANDOMIZED
MaskingQUADRUPLE
PurposeTREATMENT
Interventions
NameTypeDescription
Tapentadol oral solution 4 mg/mLDRUGParticipants aged 6 months to less than 18 years old with a body weight below 20 kg received tapentadol oral solution 4 mg/mL by mouth every 4 hours for up to 72 hours. Participants from birth to less than 6 months received tapentadol oral solution, diluted 4 fold.
Tapentadol oral solution 20 mg/mLDRUGParticipants aged from 6 months to less than 18 years with a body weight greater than or equal to 20 kg received tapentadol oral solution 20 mg/mL by mouth every 4 hours for up to 72 hours.
PlaceboOTHERMatching placebo oral solution was administered by mouth every 4 hours up to 72 hours.
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